Autologous Cell Culture: Applications and Future Prospects

The use of autologous cell culture for treatment has been increasing in recent years, particularly in the field of regenerative medicine. “Autologous cells” means the cells collected from a patient’s own skin, blood, born marrow, fat, etc.

Here are some examples as follows:

Regenerative Medicine

● Skin: Cultured autologous skin grafts are used for treating skin burns and ulcers treatment.

✔ For extensive burns, a small portion of skin sample is taken from the patient and cultured to create skin sheets for transplantation. This promotes healing and reduces scar formation.

● Cartilage: Autologous chondrocyte implantation has been developed to treat diseases like osteoarthritis.

✔ It repairs damaged cartilage and improves joint function.

● Cornea: Cultured autologous corneal epithelial cell has been researched for treating corneal damage and diseases.

✔ This can contribute to eyesight restoration.

● Cardiac Muscle: Cultured autologous cardiomyocyte has been researched for treating heart attacks and other cardiac (cardiovascular) diseases.

✔ The goal is to recover heart function.

● Nerves: Cultivating and transplanting autologous nerve cell has been researched as potential treatment for spinal cord injuries.

✔ This aims to recover motor nerve and sensory function.

Cancer Treatment

● Immune Cell Therapy: Patient’s own immune cells are cultured and activated outside the body and then reintroduced to attack cancer cells.

✔ CAR-T cell therapy, in particular, has shown significant efficacy against blood cancers.

Cosmetics

● Wrinkle Treatment: Cultured autologous fibroblast has been researched to reduce wrinkles by injection.

✔ This stimulates the production of collagen and hyaluronic acid, which improve　skin elasticity.

Other Applications

● Periodontal Disease Treatment: Research is underway to use cultured autologous gingival cells to promote periodontal tissue regeneration.

● Diabetes Treatment: Culturing and transplanting autologous islet cell has been researched to recover insulin production.

Future Prospects

Autologous cell culture is expected to be used for treatments of various fields, including regenerative medicine and cancer treatments. Combining this technology with stem cell technologies like iPS cells could further expand its therapeutic applications.

Products of WAKEN B TECH for autologous cell culture

1. MINIcell 35SE portable CO2 incubator

   

   MINIcell 35SE is a small incubator designed to be easily used even in a small laboratory, and it is also　suitable for personal use! It can support cell culture experiments with new functionalities, also the advantages inherited from old model are still taken over.
2. MINIcell(16L) portable CO2 incubator

   

   MINIcell is small size CO2 incubator. Not only is it suitable for short term and small-scale incubation, but it also can be installed in a clean bench or small space thanks to its small footprint. MINIcell will expand the possibility of your research in various fields.
3. Disposable Cell Culture Dish Ingens

   

   Ingens is a large-scale disposable cell culture dish which completely fits for MINIcell 35SE. 24-layer flask’s surface area is almost the same as 30ea of 90mm dish(1,718㎡). Easy to use, economic and compact in design.
4. Portable CO2 Gas tester GT100

   

   Regular check of CO2 concentration inside incubators is very important daily routine for cell culture. This portable CO2 gas tester is developed by us, WAKEN B TECH, and manufactured in Japan. It is easy to carry it around thanks to its compact design, and this device is suitable for daily or periodic check of CO2 concentration in your incubator. With the color LCD screen, it is easy to see the information on the screen, and an operator can use the device with simple operation in an intuitive way.
5. NeXCell P870 large capacity incubator

   

   Because of the increasing needs for regenerative medicine and cell therapy, CO2 incubator has been drawing more attention. We believe that our “NeXCell P870″ (NP870) contributes to efficient cell, virus, protein and exosome productions optimized with cell culture method. NP870 can accommodate 30 pieces of 10-layer flask (6 pieces on one shelf). Also, it has HEPA filter to reduces contamination risks.

Note:

• The examples listed above include treatments that are currently in clinical use, under research, or available only at limited medical institutions.
• The information provided above is the latest as of February 2025. We assume no responsibility for its latest or accuracy. Please note that this information may be updated in the future. So it is essential to refer to other latest sources.